Ana Ramírez de Molina Selected Research

Choline Kinase

1/2013	Combined 5-FU and ChoKα inhibitors as a new alternative therapy of colorectal cancer: evidence in human tumor-derived cell lines and mouse xenografts.
1/2008	Choline kinase as a link connecting phospholipid metabolism and cell cycle regulation: implications in cancer therapy.
10/2007	Expression of choline kinase alpha to predict outcome in patients with early-stage non-small-cell lung cancer: a retrospective study.
1/2006	Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of the choline kinase inhibitor MN58b in human carcinoma models.
7/2005	Choline kinase is a novel oncogene that potentiates RhoA-induced carcinogenesis.
9/2004	Choline kinase activation is a critical requirement for the proliferation of primary human mammary epithelial cells and breast tumor progression.
1/2003	Phospholipase D and choline kinase: their role in cancer development and their potential as drug targets.
8/2002	Overexpression of choline kinase is a frequent feature in human tumor-derived cell lines and in lung, prostate, and colorectal human cancers.
6/2002	Increased choline kinase activity in human breast carcinomas: clinical evidence for a potential novel antitumor strategy.

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Ana Ramírez de Molina Research Topics

Disease

36	Neoplasms (Cancer) 02/2021 - 01/2002
12	Colorectal Neoplasms (Colorectal Cancer) 11/2020 - 01/2009
10	Colonic Neoplasms (Colon Cancer) 01/2019 - 01/2013
7	Carcinogenesis 01/2020 - 06/2002
6	Breast Neoplasms (Breast Cancer) 02/2021 - 06/2002
5	Obesity 01/2022 - 12/2019
4	Inflammation (Inflammations) 01/2022 - 08/2019
4	Metabolic Syndrome (Dysmetabolic Syndrome X) 02/2021 - 12/2014
4	Pancreatic Neoplasms (Pancreatic Cancer) 01/2019 - 01/2014
3	Insulin Resistance 02/2021 - 12/2019
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 12/2020 - 10/2007
2	Infections 01/2022 - 01/2020
2	COVID-19 01/2022 - 01/2020
2	Cardiovascular Diseases (Cardiovascular Disease) 12/2020 - 12/2019
2	Neoplasm Metastasis (Metastasis) 10/2018 - 01/2009
2	Lung Neoplasms (Lung Cancer) 04/2017 - 10/2007
2	Carcinoma (Carcinomatosis) 07/2010 - 01/2006
1	Genetic Risk Score 03/2021
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 03/2021
1	Glioblastoma (Glioblastoma Multiforme) 12/2020
1	Adenocarcinoma 01/2020
1	Weight Gain 01/2020
1	Pediatric Obesity 01/2020
1	Hypercholesterolemia 12/2019
1	Atherosclerosis 10/2018
1	Ovarian Epithelial Carcinoma 01/2018
1	Ovarian Neoplasms (Ovarian Cancer) 01/2018
1	Hypoxia (Hypoxemia) 02/2016

Drug/Important Bio-Agent (IBA)

10	LipidsIBA 01/2022 - 01/2016
10	Biomarkers (Surrogate Marker)IBA 02/2021 - 01/2006
9	EnzymesIBA 12/2020 - 07/2005
9	Choline KinaseIBA 01/2013 - 06/2002
7	Pharmaceutical PreparationsIBA 12/2019 - 01/2003
4	Coenzyme A Ligases (Acid-Thiol Ligases)IBA 12/2020 - 11/2015
3	Fatty Acids (Saturated Fatty Acids)IBA 10/2021 - 01/2016
3	Stearoyl-CoA DesaturaseIBA 01/2019 - 11/2015
3	Protein Isoforms (Isoforms)IBA 01/2019 - 12/2008
3	GlycosyltransferasesIBA 01/2018 - 01/2014
3	Paclitaxel (Taxol)FDA LinkGeneric 04/2016 - 06/2014
3	Fluorouracil (Carac)FDA LinkGeneric 01/2015 - 01/2013
3	Phosphorylcholine (Phosphocholine)IBA 07/2010 - 06/2002
3	Choline (Choline Chloride)IBA 07/2010 - 06/2002
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 12/2020 - 04/2017
2	Proteins (Proteins, Gene)FDA Link 12/2020 - 01/2019
2	AcidsIBA 11/2020 - 05/2015
2	DiterpenesIBA 08/2019 - 01/2014
2	PolyphenolsIBA 01/2018 - 05/2015
2	PhytochemicalsIBA 01/2017 - 09/2013
2	1,4- (4- 4'- Bis- ((4- (dimethylamine)pyridinium- 1- yl) methyl)diphenyl)butane dibromideIBA 01/2013 - 01/2006
2	Protons (Proton)IBA 07/2010 - 01/2006
2	Phosphorus (Red Phosphorus)IBA 07/2010 - 01/2006
2	ras ProteinsIBA 04/2004 - 01/2002
1	Apolipoprotein E2IBA 01/2022
1	Apolipoproteins E (ApoE)IBA 01/2022
1	Lipoproteins (Lipoprotein)IBA 01/2022
1	Protease Inhibitors (Protease Inhibitor)IBA 11/2021
1	Serine (L-Serine)FDA Link 11/2021
1	Olive OilIBA 02/2021
1	AdiponectinIBA 02/2021
1	LeptinIBA 02/2021
1	Simvastatin (Zocor)FDA LinkGeneric 12/2020
1	Peptides (Polypeptides)IBA 12/2020
1	SaponinsIBA 11/2020
1	Adenosine Triphosphate (ATP)IBA 10/2020
1	Small Untranslated RNAIBA 10/2020
1	secretin receptorIBA 01/2020
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2020
1	Mitochondrial Proton-Translocating ATPases (Mitochondrial ATP Synthase)IBA 01/2020
1	Glycerides (Acylglycerol)IBA 01/2020
1	EdaravoneIBA 01/2020
1	Leptin ReceptorsIBA 01/2020
1	Trefoil FactorsIBA 01/2020
1	SerpinsIBA 01/2020
1	Surface-Active Agents (Surfactants)IBA 01/2020
1	Glucose (Dextrose)FDA LinkGeneric 12/2019
1	Insulin (Novolin)FDA Link 12/2019
1	LipopolysaccharidesIBA 08/2019
1	Tumor Protein p73IBA 01/2019
1	AutoantibodiesIBA 01/2019
1	Metformin (Glucophage)FDA LinkGeneric 01/2019
1	CholesterolIBA 10/2018
1	Caveolin 1IBA 10/2018
1	apabetaloneIBA 10/2018
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 10/2018
1	Anticarcinogenic AgentsIBA 09/2018
1	Plant ExtractsIBA 09/2018
1	serinolIBA 01/2018
1	Growth InhibitorsIBA 01/2018
1	Phosphotransferases (Kinase)IBA 01/2018
1	Folic Acid (Vitamin M)FDA LinkGeneric 09/2017
1	CeruleninIBA 04/2017
1	Bevacizumab (Avastin)FDA Link 04/2016
1	MicroRNAs (MicroRNA)IBA 02/2016
1	Acyl Coenzyme A (Acyl CoA)IBA 01/2016
1	3' Untranslated Regions (3' UTR)IBA 01/2016
1	ApolipoproteinsIBA 01/2016

Therapy/Procedure

20	Therapeutics 12/2020 - 04/2004
7	Drug Therapy (Chemotherapy) 10/2021 - 06/2014
3	Precision Medicine 01/2020 - 01/2018
1	Mediterranean Diet 02/2021